Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
Trimethyl Orthovalerate is used in the synthesis of dihydropyran-4-ones, via the Maitland-Japp reaction, which can be converted stereoselectively into tetrahydropyran-4-ones. This conversion is useful in the study of the functionalized tetrahydropyran units that are found in the anticancer polyketide lasonolide A and the Civet fragrance which is used in perfumery.
参考文献
Clarke, P., et al.: Org. Biomol. Chem., 13, 4743 (2015)