4-Iodobut-1-ene is a reagent in the design of cell-permeable stapled peptides which are used as HIV-1 integrase inhibitors. 4-Iodobut-1-ene is also used as a reagent in the synthesis of pyrrolopyridazines as novel DGAT1 inhibitors.
参考文献
Long, Y., et al.: J. Med. Chem., 56, 5601 (2013); Fox, B.M., et al.: Bioorg. Med. Chem. Lett., 20, 6030 (2010)
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