Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用
7-Chloro-3-iodo-4-quinolinol is an intermediate in the synthesis of 3-Trifluoromethyl Hydroxychloroquine (T815840), an impurity of Hyroxychloroquine (B419750); an antimalarial; antirheumatic; lupus erythematosus suppressant. It is a COVID19-related research product.
参考文献
Yarden, Y., et al.: Nature, 323, 226 (1986), Seifert, R., et al.: J. Biol. Chem., 264, 8771 (1989), Gahl, W., et al.: Mol. Genet. Metab., 76, 234 (2002), Card, J., et al.: Toxicol. Sci., 75, 169 (2003),
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