Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
5-Amino-1-methyl-1H-Benzimidazole-2-propanol is an intermediate used in the synthesis of 4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid (C367195), which is a degradation production of Bendamustine (B132500), which is used as an anticancer drug.
参考文献
Bremer, K., et al.: Tumordiagn. Ther., 17, 1 (1996); Barman Balfour, J.A., et al.: Drugs, 61, 631 (2001)
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