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产品编号
1237880
CAS 号
19916-73-5
中文名称
6-(苄氧基)-9H-嘌呤-2-胺（恩替卡韦杂质）
MDL 号
MFCD00269931
分子量
241.25
存储条件
2-8°C, protect from light
网页展示纯度为入库指导纯度值，各批次间存在一定差异，实际纯度以收货为准
熔点
205-210 °C
沸点
459.3±55.0 °C at 760 mmHg
闪点
旋光
描述
TPSA
89.71
LogP
1.5141
H_Acceptors
5
H_Donors
2
Rotatable_Bonds
3
[1]. Anna M Urban, et al. Formation and repair of pyridyloxobutyl DNA adducts and their relationship to tumor yield in A/J mice. Chem Res Toxicol. 2012 Oct 15;25(10):2167-78.
[2]. George C Bobustuc, et al. MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy. Mol Med. 2012 Sep 7;18(1):913-29.
[3]. Holly J Meany, et al. Pharmacokinetics of temozolomide administered in combination with O6-benzylguanine in children and adolescents with refractory solid tumors. Cancer Chemother Pharmacol. 2009 Dec;65(1):137-42.
[4]. Narin Apisarnthanarax, et al. Phase I clinical trial of O6-benzylguanine and topical carmustine in the treatment of cutaneous T-cell lymphoma, mycosis fungoides type. Arch Dermatol. 2012 May;148(5):613-20.
[5]. Rui Zhu, et al. 4-nitrobenzyloxycarbonyl derivatives of O(6)-benzylguanine as hypoxia-activated prodrug inhibitors of O(6)-alkylguanine-DNA alkyltransferase (AGT), which produces resistance to agents targeting the O-6 position of DNA guanine. J Med Chem. 2011 Nov 10;54(21):7720-8.
警示图
警示词
Warning
危险申明
H315-H319-H335
警告申明
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
GHS 编码
GHS07
1025049 现货
￥ ȀƏƄƞƞ -5g
1065391 现货
￥ ǯŔŔƄƞƞ -100mg
1230049 货期咨询
￥ ǕșǕŔƄƞƞ -1g
1770387 货期咨询
1275456 货期咨询
￥ ǕǯƞƄƞƞ -5g
现货供应
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