Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用
Trimethylsilylpropargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.
参考文献
Lima, L., et al.: Curr. Med. Chem. Anti Inflamm. Anti Allergy Agents, 3, 9 (2004); Terashita, Z., et al.: Thromb. Res., 77, 411 (1995)
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