2-(4-Hydroxyphenoxy)acetic Acid is used in the design, synthesis and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hyroxyphenylpyruvate dioxygenase. Acts as a reagent in the preparation, anti-HIV and kinesin Eg5 inhibitory activities, QSAR, and modeling studies of triazolothiadiazole and triazolothiadiazine derivatives. Synthesis of thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties.
参考文献
Lin Y., et al.: Bioorg. Med. Chem. lett., 12, 1709 (2002); Khan, I., Z. Naturforsch. B: J. Chem. Sci., 70, 47 (2015); Castelino, P. A., et al.: Eur. J. Med. Chem., 84, 194 (2014)
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