Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用
2-Furanyl-1-piperazinylmethanone (Terazosin EP Impurity L) was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.
参考文献
Bastien, D., et al.: J. Med. Chem., 55, 3182 (2012); Giardina, D., et al.: J. Med. Chem., 28, 1354 (1985);
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