tert-Butyl Oxobutyrate is a chemical reagent used in the preparation of a potent Bcl-2/Bcl-xL inhibitor used in tumor inhibition. Also used in the synthesis of potent small molecule-peptide conjugates in HIV-1 inhibition.
参考文献
Aguilar, A. et al.: J. Med. CHem., 56, 3048 (2013); Wang, C. et al.: J. Med. Chem., 56, 2527