2-Bromo-1-cyclopropylethanone is an intermediate used to prepare pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A3 adenosine receptor antagonists. It is also used to synthesize indolizine derivatives incorporating a cyclopropylcarbonyl group against Hep-G2 cancer cell line.
参考文献
Baraldi, P., et al.: J. Med. Chem., 48, 4697 (2005); Shen, Y., et al.: Eur. J. Med. Chem., 45, 3184 (2010)
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