Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
3-Amino-3-methylbutanoic Acid acts as a reagent in the preparation of arylsulfonyl methylbutanamides of cycloalkylamines, particularly adamantylamines, as selective inhibitors of human and murine 11b-hydroxysteroid dehydrogenase type 1. Synthesis of acetylcholine and carbamoylcholine analogs as a functionally selective a4b2 nicotinic acetylcholine receptor agonist. Phenamide preparation by coupling reaction.
参考文献
Lee, Y., et al.:Bioorg. Med. Chem. Lett., 24, 1421 (2014); Hansen, C. P., et al.: J. Med. Chem., 51, 7380 (2008); Makkar, N. S., et al.: J. Antibiot., 48, 369 (1995)
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