8-Aminoadenine is used in the synthetic preparation of purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase. It can also be useful in label-free biosensing of RNA, and in the study of structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors.
参考文献
Young, R.C. et al.: J. Med. Chem., 33, 2073 (1990); Carrascosa, L. G., et al.: Nucleic Acids Res., 40, 56 (2012); Borrmann, T., et al.: J. Med. Chem., 52, 5974 (2009)
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